Ingredients

Valine

What valine does as a conditioning amino acid in skincare blends, why it isn't an exfoliating acid, and who it suits.

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Also known as L-Valine

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Chemical structure of Valine (C5H11NO2)
Chemical structure of Valine (C₅H₁₁NO₂), drawn from PubChem CID 6287.

Quick facts

INCI name
Valine
CAS number
72-18-4
Origin
Biotech (fermentation) or Synthetic
Chemical class
Amino acid
What it does in a formula
skin conditioning, humectant, hair conditioning
Why it is in the formula
Usually one of several amino acids in a blend that helps a formula hold water and leave a conditioned feel.
Regulatory notes
The Cosmetic Ingredient Review panel concluded that alpha-amino acids, including valine, are safe in the present practices of use and concentration in cosmetics.

What is Valine?

Valine is one of the amino acids your body uses to build proteins. Cosmetic valine is usually made by fermentation or chemical synthesis, and the label name doesn’t tell you which.

Valine is one of the three branched-chain amino acids, along with isoleucine and leucine. On labels it nearly always appears next to them and other amino acids in a blend.

On a label it usually sits in a group with other amino acids, such as glycine, alanine, serine, proline and aspartic acid. You’ll find it in serums, toners, moisturizers and some hair products.

What does Valine do?

  • Conditions skin. The safety review describes amino acids as working mainly as skin and hair conditioning agents.
  • Helps hold water. Amino acids are also listed as humectants, so they help a product hold moisture at the skin’s surface.
  • Rounds out a blend. Alongside other amino acids and humectants, it adds to a soft, hydrated finish.

It’s a supporting ingredient. The safety review reported it at no more than about 1% in cosmetics, so it isn’t a reason to buy a product on its own.

Who is Valine for?

It suits most skin types, including dry and sensitive skin. The safety panel reviewed alpha-amino acids as a group and concluded they are safe as used in cosmetics.

The “acid” in “amino acid” sometimes worries people with sensitive skin. Valine isn’t an exfoliating acid. If a product that lists it stings, other ingredients in the formula, such as fragrance or an exfoliating acid, are more likely to be responsible. Patch-test new products if your skin reacts easily.

What to pair Valine with, and what to avoid

It already sits alongside other amino acids and humectants such as glycerin and hyaluronic acid in most formulas. There’s nothing you need to avoid with it, and you don’t need a separate valine product.

Quick picks with Valine

Picked from label facts only. We haven't tested these products.

All 17 products with Valine

Daily Moisturizers & Water Gel Creams (2)

Hydrating Toners, Essence Waters & Face Mists (2)

Eye Creams & Under-Eye Patches (2)

Gel, Foam & Cream Facial Cleansers (1)

Hydrating Serums, Essences & Ampoules (1)

From stores: products with Valine

Store-listed products whose ingredient list we've checked.

Hydrating Serums, Essences & Ampoules (6)

Hydrating Toners, Essence Waters & Face Mists (1)

Mineral Pressed Powders & Skin-Nourishing Primers (2)

Common questions

What does valine do in skincare?

It's an amino acid used as a skin-conditioning ingredient and humectant. It helps the formula hold water and leaves skin feeling softer, usually as part of a blend with other amino acids.

Is valine an exfoliating acid?

No. The word acid refers to its chemistry as an amino acid. In skincare it's used for conditioning and water-binding, not to exfoliate like glycolic or salicylic acid.

Is valine safe for skin?

A cosmetic safety panel concluded alpha-amino acids, including valine, are safe as used in cosmetics. As with any product, stop using one that stings or leaves you red.

Why do some labels list so many amino acids?

Some formulas add a blend of amino acids rather than a single one. Each one contributes a little to the conditioning, water-holding feel. No single one, valine included, is the reason to buy the product.

Sources