Squalane
What squalane does in skincare, how it softens and seals in moisture, who may enjoy its feel, and how to layer it.
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What it is
Squalane is an emollient used to soften skin and help reduce moisture loss. It is the stable, hydrogenated form of squalene, a lipid found naturally in skin and in some plant and animal sources. Cosmetic squalane is commonly derived from plant sources, though sourcing can vary by manufacturer. Check product information if source matters to you.
Squalane often appears in facial oils, moisturizers, and other products marketed for a smooth, lightweight feel. Despite being called an oil in some descriptions, its texture can feel less heavy than many traditional facial oils. The base formula and amount used still make a difference.
What it does
- Softens the skin. Squalane is an emollient that helps leave skin feeling smooth and supple.
- Helps reduce moisture loss. It can add an oil-like layer that slows water escaping from the skin’s surface.
- Fits into many product types. It appears in standalone oils as well as creams and lotions, so you can choose the texture you prefer.
Who it suits
Squalane may suit dry or combination skin, or anyone who likes an emollient finish. Some people with oily skin also prefer it to heavier oils, but that is a personal texture preference, not a guarantee about how your skin will respond. If you tend to clog or dislike a slick finish, start with a small amount or look for a lighter moisturizer that includes squalane in a blend.
Squalane is generally considered a well-tolerated cosmetic ingredient. Still, reactions can happen, and the rest of the formula may include ingredients that do not suit you. Patch-test a new product if your skin is sensitive. You do not need to add a face oil if your current moisturizer already does the job; more layers are not automatically more effective.
What to pair it with, and what not to
Squalane can be applied after water-based products such as hyaluronic acid or glycerin, then followed by other steps according to texture and directions. It can also be included in a moisturizer with ceramides. It is compatible with common actives such as retinol, though it cannot guarantee retinol will not irritate. Use only as much as feels comfortable, and apply sunscreen as directed during the day.
Skin Realist check: If a lighter moisturizer already works for you, you do not have to graduate to an oil just because it sounds luxurious.
Quick picks with Squalane
Scent-free, no patch-test flags on the label
COSRX The Vitamin C 13 Serum
Ascorbic Acid (Vitamin C) 13% · scent-free label
AmazonBrand lists it for sensitive skin
Dermalogica dynamic skin retinol serum
Retinoid Complex 3.5% · oily, dry, combination, sensitive, normal skin · scented
AmazonBrand lists it for oily skin
Laneige Balance Mode Shine Control Weightless Moisturizer
Rice bran water, niacinamide, squalane, madecassoside, and rice ferment · oily, combination, sensitive, normal skin · scent-free label
Amazon
All 76 products with Squalane
Daily Moisturizers & Water Gel Creams (22)
Laneige Balance Mode Shine Control Weightless MoisturizerAmazon
Sulwhasoo Concentrated Ginseng Rejuvenating CreamAmazon
Sulwhasoo Skin Strengthening Emulsion for MenAmazon
Dermalogica biolumin-c vitamin c gel moisturizerAmazon
Sunday Riley C.E.O. Vitamin C Rich Hydration CreamAmazon
Elemis Daily Moisture BoostAmazon
Dermalogica phyto nature oxygen creamAmazon
Dermalogica skin soothing hydrating lotionAmazon
COSRX The Blue Peptide Bakuchiol Plump Bounce CreamAmazon
Laneige Water Bank Blue Hyaluronic Cream MoisturizerAmazon
Dermalogica acne biotic moisturizerAmazon
Perricone MD Cold Plasma Plus+ Advanced Hydrating ComplexAmazon
Perricone MD Cold Plasma Plus+ Sub-D/NeckAmazon
Sulwhasoo Concentrated Ginseng Rejuvenating Cream RichAmazon
Sulwhasoo Essential Firming Cream EXAmazon
Perricone MD High Potency Hyaluronic Intensive MoisturizerAmazon
Dermalogica multivitamin power recovery creamAmazon
Laneige Perfect Renew 3x Cream AdvancedAmazon
Dermablend Prebiotic Daily MoisturizerAmazon
Elemis Pro-Collagen Morning MatrixAmazon
Elemis Pro-Collagen Overnight MatrixAmazon
Elemis ULTRA SMART Pro-Collagen Night GeniusAmazon
Eye Creams & Under-Eye Patches (7)
Sulwhasoo Concentrated Ginseng Rejuvenating Eye CreamAmazon
Dermalogica phyto nature lifting eye creamAmazon
Sulwhasoo First Care Activating Eye SerumAmazon
Perricone MD High Potency Triple Retinol Renewal Eye SerumAmazon
Perricone MD Hypoallergenic Clean Correction Firming & Brightening Eye CreamAmazon
Perricone MD Hypoallergenic Firming Eye CreamAmazon
Dermalogica smart eye density undereye serumAmazon
Targeted Vitamin C & Brightening Correctors (6)
Anti-Aging & Retinoid Serums (6)
Dermalogica dynamic skin retinol serumAmazon
Perricone MD High Potency Triple Retinol Renewal SerumAmazon
COSRX The Retinol 0.5 OilAmazon
Dermalogica dynamic skin strengthening serumAmazon
Perricone MD High Potency Retinol Recovery Overnight MoisturizerAmazon
Perricone MD Neuropeptide Firming Facial ConcentrateAmazon
Hydrating Serums, Essences & Ampoules (6)
Laneige Water Bank Blue Hyaluronic SerumAmazon
Dermalogica stabilizing repair face + body serumAmazon
Perricone MD High Potency Hyaluronic Intensive Hydrating SerumAmazon
Perricone MD High Potency Intensive Smoothing SerumAmazon
Elemis Pro-Collagen Future Restore SerumAmazon
Jane Iredale HydroPure Color Correcting Serum with Hyaluronic Acid & CoQ10Amazon
Premium Overnight Recovery Packs & Sleeping Facials (3)
Skin Barrier Repair Creams & Recovery Jars (3)
High-Definition Camouflage Concealers (3)
Body Creams, Butters & Body Oils (2)
Hydrating Toners, Essence Waters & Face Mists (2)
Dermatological Acne & Chemical Exfoliating Liquids (2)
Daily Sunscreens & SPF Moisturizers (2)
Intensive Lip Recovery Masks & Tinted Balms (2)
Lipsticks, Glosses & Lip Liners (2)
Full-Coverage Camouflage & Liquid Foundations (2)
Face Oils & Treatment Oils (1)
Premium Double-Cleansing Balms & Melting Gels (1)
Gel, Foam & Cream Facial Cleansers (1)
Cream & Gel Treatment Masks (1)
Sheet, Hydrogel & Clay Masks (1)
Blush, Bronzers & Highlighters (1)
Common questions
What does squalane do for skin?
Squalane is an emollient that helps soften skin and reduce moisture loss. It is used in facial oils, moisturizers, and other products, often for a lightweight, smooth feel.
Is squalane the same as squalene?
No. Squalene is an unsaturated oil naturally found in skin and some plant or animal sources. Squalane is its more stable, hydrogenated form commonly used in skincare.
Is squalane oil good for oily skin?
Squalane can feel lighter than many oils, so some people with oily or combination skin enjoy it. Preferences vary, and you can choose a light moisturizer instead if oils feel too rich.
Can you use squalane with retinol?
Yes. Squalane can be layered with retinol as part of a moisturizing routine. It does not prevent all irritation, so use retinol gradually and follow product directions.
