High Potency Triple Retinol Renewal Serum

What it is

Perricone MD describes this as a day-and-night face serum for all skin types concerned with wrinkles, uneven texture, and dullness. The ingredient list includes retinol and retinyl linoleate; the brand describes its featured blend as triple retinol.

Key ingredients

• Triple retinol blend: Perricone MD says its blend of encapsulated retinol, retinol ester, and phyto-retinol supports skin renewal and helps reduce the look of fine lines and uneven texture.
• Coenzyme Q10: The brand describes this antioxidant as helping reduce the appearance of dullness and discoloration.
• Beta-carotene: Perricone MD says this provitamin A helps support the blend and reduce the look of redness and uneven texture.

How to use

Use morning and evening after cleansing. Massage over the face and neck with a gentle upward motion and let it absorb. Perricone MD recommends SPF after morning use.

Who should be careful

The ingredient list includes retinol and retinyl linoleate. Anyone who knows they are sensitive to retinoids should take care when considering this formula. This is general product information, not medical advice.

What the brand claims

Perricone MD reports increased surface skin renewal in 3 days in a clinical study of 38 women. This is a brand-reported result, not an independent finding by us.

A facial serum with retinol, retinyl linoleate and niacinamide.

Manufacturer ingredient information

Manufacturer ingredient list

Water/Aqua/Eau, Glycerin, Dimethicone, Propanediol, Squalane, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Niacinamide, Rubus Idaeus (Raspberry) Seed Oil, Lactobacillus Ferment, Phenoxyethanol, Polyacrylate Crosspolymer-6, Pentylene Glycol, Caprylic/Capric Triglyceride, Ethylhexylglycerin, Linum Usitatissimum (Linseed) Seed Extract, Tetrasodium Glutamate Diacetate, Mannose, Sodium Mannose Phosphate, Ceramide NP, Allantoin, Aloe Barbadensis Leaf, Bisabolol, Retinol, Polysorbate 20, Lecithin, Polysorbate 60, Sorbitan Isostearate, Chlorella Vulgaris Extract, Hydrogenated Phosphatidylcholine, Lysolecithin, Retinyl Linoleate, Hydroxyphenyl Propamidobenzoic Acid, Cetyl Palmitate, Laureth-23, Sodium Hyaluronate Crosspolymer, Tocopheryl Acetate, Glyceryl Caprylate, P-Anisic Acid, Glycine Soja (Soybean) Oil, Sodium Hydroxide, Sodium Hyaluronate, Thioctic Acid, Trideceth-6 Phosphate, Sodium Acetylated Hyaluronate, Ubiquinone, Tocopherol, Citric Acid, Hyaluronic Acid, Hydrolyzed Glycosaminoglycans, Hydrolyzed Sodium Hyaluronate, 1,2-Hexanediol, Lactic Acid, Sodium Benzoate, Ascorbyl Palmitate, Potassium Sorbate, Hydrolyzed Hyaluronic Acid, Beta-Carotene, Daucus Carota Sativa (Carrot) Root Extract, Phytic Acid, Caprylhydroxamic Acid, Beta-Sitosterol, Squalene, Arginine/Lysine Polypeptide

Verified ingredient flags: None of the tracked ingredients identified in this published list.

Source: https://www.perriconemd.com/p/high-potency-triple-retinol-renewal-serum/15374146/ (checked 2026-10-11).

Check the current package ingredient list before use; manufacturer formulas may change. Ingredient flags are presence checks, not safety judgments.

Sources

• https://www.perriconemd.com/p/high-potency-triple-retinol-renewal-serum/15374146/ (checked 2026-10-11)

We have not tested this product.