Neuropeptide Firming Facial Concentrate

What it is

This lightweight facial concentrate is designed to support firmer, more elastic-looking skin. Perricone MD says it targets sagging, visible loss of contour, and a softer, less sculpted-looking complexion.

Key ingredients

• Dimethyl MEA: The product page calls this a key ingredient that supports smoother, firmer-looking skin.
• Squalane: Perricone MD lists squalane as a moisturizing ingredient that helps cushion and support the skin barrier.
• Glycerin: The brand highlights glycerin as a humectant that helps skin feel hydrated and comfortable.
• Peptides: The official product copy calls out neuropeptides and biomimetic growth-factor peptides for visible firmness and elasticity support.

How to use

Use the concentrate as a daily anti-aging step. Perricone MD describes it as a lightweight cream that helps visibly lift and firm the look of the skin over time.

Who should be careful

The official page describes a floral rose-bergamot scent, and the ingredient list includes glycolic acid and benzyl alcohol. Those sensitive to fragrance or acids may prefer a patch test before regular use.

What the brand claims

Perricone MD says the concentrate visibly reduces sagging skin and supports firmness, contour, elasticity, and volume. The page also highlights neuropeptides, biomimetic growth-factor peptides, and plant stem cells as part of the firming strategy.

Sources

• https://www.perriconemd.com/p/neuropeptide-firming-facial-concentrate/15374142/ (checked 2026-10-11)

A facial concentrate formulated with squalane, glycerin and dimethyl MEA.

Manufacturer ingredient information

Manufacturer ingredient list

Water/Aqua/Eau, Caprylic/Capric Triglyceride, Squalane, Glycerin, Dimethyl MEA, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glycolic Acid, Phosphatidylcholine, Propanediol, Silica, Citric Acid, C15-19 Alkane, Benzyl Alcohol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Pullulan, 1,2-Hexanediol, Mannitol, Hydrogenated Lecithin, Tocopheryl Acetate, Synthetic Fluorphlogopite, Tocopherol, Glycine Soja (Soybean) Oil, Mica, Lauryl Glucoside, Xanthan Gum, Althaea Officinalis Root Extract, Butylene Glycol, Caprylhydroxamic Acid, Malus Domestica Fruit Cell Culture Extract, Crocus Sativus (Saffron) Flower Extract, Phenoxyethanol, Sodium Hyaluronate, Tin Oxide, Caprylyl Glycol, Ascorbyl Palmitate, Sodium Lactate, Lecithin, Carbomer, Acetyl sh-Hexapeptide-5 Amide Acetate, Cyanocobalamin, Coco-Glucoside, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Arginine/Lysine Polypeptide, Titanium Dioxide (CI 77891)

Verified ingredient flags: None of the tracked ingredients identified in this published list.

Source: https://www.perriconemd.com/p/neuropeptide-firming-facial-concentrate/15374142/ (checked 2026-10-11).

Check the current package ingredient list before use; manufacturer formulas may change. Ingredient flags are presence checks, not safety judgments.

We have not tested this product.