Cold Plasma Plus+ Hand Therapy

What it is

Perricone MD describes this as a silky hand treatment for the look of thin, discolored and rough-textured hands. The brand says it is intended for all skin types, particularly hands with dryness, crepey texture, discoloration or visible lines.

Key ingredients

• Shea butter: Perricone MD says its vitamins A, E and F help moisturize and nourish hands for a softer, smoother-looking appearance.
• Phospholipids: The brand describes these as supporting the skin barrier and helping keep hands hydrated.
• Glycine: Perricone MD says this amino acid supports moisture retention and helps reduce the look of lines.

How to use

Apply liberally to the fingers and backs of the hands, then massage in. Perricone MD says to use it morning, evening and throughout the day as desired.

What the brand claims

Perricone MD reports that, in a clinical study of 40 men and women after eight weeks, 100% showed improvement in skin hydration and barrier function, 97% in the appearance of radiance and tightness, and 80% in the appearance of crepiness. These are brand-reported results, not our findings.

Who should be careful

The current manufacturer ingredient list does not include a fragrance or parfum entry. Anyone with a known ingredient sensitivity should review the current package list; this is general product information, not medical advice.

A hand cream in the Cold Plasma Plus+ range.

Manufacturer ingredient information

Manufacturer ingredient list

Water/Aqua/Eau, Hydroxyethyl Urea, Butyrospermum Parkii (Shea) Butter, Dicaprylyl Ether, Aluminum Starch Octenylsuccinate, Butylene Glycol, Ethylhexyl Palmitate, Stearic Acid, Cetearyl Alcohol, Dimethicone, Glyceryl Stearate, Hydroxyphenoxy Propionic Acid, Palmitoyl Glycine, PEG-100 Stearate, Helianthus Annuus (Sunflower) Seed Oil, Phospholipids, Xanthan Gum, Ethylhexylglycerin, Tocopherol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Sodium Acrylates Copolymer, Polysorbate 60, Hydrogenated Polydecene, Triethyl Citrate, Polyglyceryl-10 Stearate, Phenoxyethanol

Verified ingredient flags: None of the tracked ingredients identified in this published list.

Source: https://www.perriconemd.com/p/cold-plasma-plus-plus-hand-therapy/12435660/ (checked 2026-10-11).

Check the current package ingredient list before use; manufacturer formulas may change. Ingredient flags are presence checks, not safety judgments.

Sources

• https://www.perriconemd.com/p/cold-plasma-plus-plus-hand-therapy/12435660/ (checked 2026-10-11)

We have not tested this product.