Perricone MD
Neuropeptide Eyelid Lift Serum
A lightweight serum for the eyelid area with peptides and caffeine.
- Fragrance free

What it is
Perricone MD Neuropeptide Eyelid Lift Serum is a lightweight eye-area serum intended to smooth and firm the eyelid area. The brand says it targets drooping eyelids, creases, and the look of sagging while leaving the skin with a velvety finish.
Key ingredients
- Neuropeptides: Perricone MD says short protein-like molecules support the look of smoother, more renewed skin.
- Biomimetic growth-factor peptides: The brand describes these as helping with elasticity and a more defined eye area.
- Acyl-glutathione: The product description names this as an antioxidant ingredient that helps target visible aging and creasing.
- Caffeine: The ingredient list includes caffeine for the eye area, and the product description says it helps wake up tired-looking skin.
How to use
The brand describes the serum as a fast-absorbing eyelid treatment. Use it on clean eyelids and the surrounding eye area as part of a routine focused on the upper eye area.
Who should be careful
This product contains lactic acid and is designed for the delicate eyelid area, so a patch test is sensible if your skin is easily irritated or if you are using other acids or retinoids. This is general information, not medical advice.
What the brand claims
Perricone MD says the serum helps reduce the look of sagging eyelids, eyelid creases, and deep wrinkles while improving firmness and smoothing eyelid texture. The official page describes a lightweight, fast-absorbing formula with a velvety finish.
Sources
- https://www.perriconemd.com/p/neuropeptide-eyelid-lift-serum/15763867/ (checked 2026-10-11)
We have not tested this product.
What's on the label
| Category | Eye Creams & Under-Eye Patches |
|---|---|
| Brand | Perricone MD |
| Form | Serum |
| Texture | Lightweight and fast-absorbing |
| Finish | Velvety |
| Key ingredients | Neuropeptides, biomimetic growth-factor peptides, acyl-glutathione, caffeine, and hyaluronic acid |
| Free from | Fragrance-free by the official product listing |
| Routine step | Eye-area treatment |
| Key ingredient | None stated |
| Best for | Not specified |
| Fragrance free | Yes |
| Worth knowing | Nothing flagged |
| Full ingredient list | Water/Aqua/Eau, 1,2-Hexanediol, Phenoxyethanol, Avena Sativa (Oat) Kernel Extract, Lactic Acid, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Sodium Hydroxide, Silica Cetyl Silylate, Sodium Polyacrylate, Citric Acid, Allantoin, Caffeine, Dimethyl MEA, Silica, Butylene Glycol, Disodium EDTA, Gentiana Lutea Root Extract, Caprylyl Glycol, Sodium Hyaluronate, Ethylhexylglycerin, S-Palmitoylglutathione, Tetrapeptide-1, Potassium Sorbate, Acetic Acid, Acetyl Hexapeptide-8, Arginine/Lysine Polypeptide, Iron Oxides (CI 77491), Titanium Dioxide (CI 77891) |
| Size | Not stated |
| Source | Brand's own product page Checked |
Common questions
What does the serum target?
Perricone MD says it helps minimize the look of drooping eyelids, eyelid creases, sagging, and crow's feet.
What does it feel like?
The official product copy describes a fast-absorbing, lightweight serum with a velvety finish.
Is it fragrance-free?
The official product metadata lists the scent as fragrance-free.
What ingredients are highlighted?
The brand calls out neuropeptides, biomimetic growth-factor peptides, acyl-glutathione, and caffeine as key ingredients.