Dermalogica
Smart Response Serum
A smart serum that hydrates, brightens, and helps calm visible redness while smoothing the look of fine lines.
- Fragrance free
- oily skin
- dry skin
- combination skin
- sensitive skin
- normal skin

What it is
Dermalogica Smart Response Serum is a next-generation serum designed to respond to skin’s changing needs with hydration, brightening, soothing, and fine-line support. The official product page says it is recommended for all skin types and is meant to help balance dryness, dehydration, pores, and visible redness.
Key ingredients
- Hydrolyzed beta glucan: The product page says this ingredient helps maintain optimal hydration.
- Hydrolyzed wheat flour: Dermalogica says this ingredient brightens and helps reduce the look of dark spots.
- Japanese Cornelia Cherry: This antioxidant-rich ingredient helps protect stressed skin and soothe the appearance of redness.
- Mannose-6-phosphate: The brand says this plant-based ingredient helps smooth skin and support a firmer appearance.
- Lactic acid: This AHA helps brighten and smooth the skin’s surface.
How to use
Apply Smart Response Serum each morning and night after cleansing and toning. The brand recommends allowing one minute for absorption before continuing your routine.
Who should be careful
This formula contains fragrance and essential-oil components, including citrus, floral, and wood-derived ingredients such as bergamot, orange peel oil, and lavender-related compounds. If you notice sensitivity to scented ingredients or acids, patch testing before full use is a sensible step. This is general product information, not medical advice.
What the brand claims
Dermalogica says Smart Response Serum helps skin maintain optimal hydration, brighten and reduce the appearance of dark spots, soothe redness, and improve the look of fine lines and wrinkles. The page describes it as a personalized-response serum that works where and when skin needs it.
Sources
- https://www.dermalogica.com/products/smart-response-serum (checked 2026-10-11)
We have not tested this product.
What's on the label
| Category | Hydrating Serums, Essences & Ampoules |
|---|---|
| Brand | Dermalogica |
| Model | 666151112148 |
| GTIN / UPC | 00666151112148 |
| Form | Serum |
| Texture | Lightweight serum |
| Key ingredients | Hydrolyzed beta glucan, hydrolyzed wheat flour, Japanese Cornelia Cherry, mannose-6-phosphate, and lactic acid |
| When to use | Morning and night |
| Routine step | After cleansing and toning |
| Key ingredient | None stated |
| Best for | oily, dry, combination, sensitive, normal skin |
| Fragrance free | Yes |
| Worth knowing | Limonene, Linalool, Geraniol, Citronellol, Coumarin |
| Full ingredient list | Water/Aqua/Eau, Glycerin, Coco-Caprylate/Caprate, PPG24-Glycereth-24, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Sodium Acrylates Crosspolymer-2, C18-36 Acid Triglyceride, Sodium Polyacryloyldimethyl Taurate, Hydroxyacetophenone, Jojoba Esters, Olive Oil Decyl Esters, Phytosterols, Cornus Officinalis Fruit Extract, Hydrolyzed Wheat Flour, Sodium Mannose Phosphate, Phytosteryl Macadamiate, Hydrolyzed BetaGlucan, Mimosa Tenuiflora Bark Extract, Ilex Paraguariensis Leaf Extract, Sea Salt, Ferula Galbaniflua (Galbanum) Resin Oil, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Juniperus Virginiana Oil, Pelargonium Graveolens Flower Oil, Vetiveria Zizanoides Root Oil, Prunus Amygdalus Amara (Bitter Almond) Kernel Oil, Chlorella Vulgaris Extract, Dipteryx Odorata Seed Extract, Lactic Acid, Bentonite, C12-18 Acid Triglyceride, Squalene, Tocopherol, Sodium Acetylated Hyaluronate, Mannose, Citric Acid, Hydrated Silica, Sodium Benzoate, Potassium Sorbate, Citronellol, Geraniol, Coumarin, Linalool, Limonene |
| Size | Not stated |
| Source | Brand's own product page Checked |
Common questions
What skin concerns does Dermalogica say it addresses?
The official page says it is recommended for all skin types and designed to target dryness, dehydration, fine lines, pores, and sensitivity or redness.
What does the brand say the serum does?
Dermalogica describes it as a next-generation smart serum that hydrates, brightens, soothes, and helps smooth the look of fine lines.
How should I use it?
The brand advises applying it each morning and night after cleansing and toning, allowing one minute for absorption.
Which ingredients are highlighted?
The product page highlights hydrolyzed beta glucan, hydrolyzed wheat flour, Japanese Cornelia Cherry, plant-based mannose-6-phosphate, and lactic acid.