Perricone MD

Neuropeptide Pro-Strength Firming Moisturizer

A rich firming face cream with peptides and ceramides for a cushiony, more elastic feel.

Published · Updated

    What it is

    This face cream is designed to cushion thinning skin and support a firmer, more elastic feel. Perricone MD positions it as a rich daily moisturizer for firmness, elasticity, and visible photodamage support.

    Key ingredients

    • Neuropeptides: Support the look of smoother, more resilient skin.
    • Biomimetic growth factor peptides: Highlighted by the brand for visible renewal and a more supported feel.
    • Ceramide NP: Helps support the skin barrier in a richer cream base.
    • Chia and macadamia seed oils: Add cushioning and hydration to the moisturizer.

    How to use

    The brand presents it as a daily moisturizer for the face and a part of a firming skincare routine. It is intended to be used as a richer cream step rather than a fast-absorbing gel.

    Who should be careful

    This formula includes fragrance and fragrance-related ingredients, including limonene and linalool. If you are sensitive to fragrance or rich cream textures, review the ingredient list before regular use.

    What the brand claims

    Perricone MD says the cream visibly restores crepey skin, strengthens the look of skin thickness, and improves firmness, plumpness, and tone over time. The page also links it to reducing the look of photodamage and dark spots.

    Manufacturer ingredient information

    Manufacturer ingredient list

    Water/Aqua/Eau, Caprylic/Capric Triglyceride, Polyhydroxystearic Acid, Triethoxycaprylylsilane, Coco-Caprylate/Caprate, Tocopherol, Glycerin, Steareth-20, Sorbitan Stearate, Cetearyl Alcohol, Polysorbate 60, C12- 15 Alkyl Benzoate, Tocopheryl Acetate, Polyester-7, Neopentyl Glycol Diheptanoate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Palmitoyl Glycine, Bisabolol, Glyceryl Stearate, Benzyl Alcohol, Caprylyl Glycol, 1,2-Hexanediol, Linum Usitatissimum Seed Oil, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Sodium Citrate, Pongamia Pinnata Seed Extract, Salvia Hispanica Seed Oil, Macadamia Ternifolia Seed Oil, Fragrance (Parfum), Sclerotium Gum,b Ceramide NP, Citric Acid, Phenoxyethanol, Potassium Sorbate, Acetic Acid, Acetyl Hexapeptide-8, S-Palmitoylglutathione, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Sodium Phytate, Citronellol, Geranyl Acetate, Hydroxycitronellal, Limonene, Linalool, Linalyl Acetate, Tetramethyl Acetyloctahydronaphthalenes

    Verified ingredient flags: Fragrance (Parfum); Limonene; Linalool; Citronellol

    Source: https://www.perriconemd.com/p/neuropeptide-pro-strength-firming-moisturizer/15763868/ (checked 2026-10-11).

    Check the current package ingredient list before use; manufacturer formulas may change. Ingredient flags are presence checks, not safety judgments.

    Sources

    We have not tested this product.

    What's on the label

    CategoryDaily Moisturizers & Water Gel Creams
    BrandPerricone MD
    Size2 fl oz / 59 mL
    FormFirming face cream
    TextureRich cream
    FinishComforting, smoothing
    Key ingredientsNeuropeptides, biomimetic growth factor peptides, chia seed oil, ceramide NP
    Routine stepDaily moisturizer
    Key ingredientNone stated
    Best forNot specified
    Fragrance freeNo
    Worth knowingFragrance (Parfum), Limonene, Linalool, Citronellol
    Full ingredient listWater/Aqua/Eau, Caprylic/Capric Triglyceride, Polyhydroxystearic Acid, Triethoxycaprylylsilane, Coco-Caprylate/Caprate, Tocopherol, Glycerin, Steareth-20, Sorbitan Stearate, Cetearyl Alcohol, Polysorbate 60, C12- 15 Alkyl Benzoate, Tocopheryl Acetate, Polyester-7, Neopentyl Glycol Diheptanoate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Palmitoyl Glycine, Bisabolol, Glyceryl Stearate, Benzyl Alcohol, Caprylyl Glycol, 1,2-Hexanediol, Linum Usitatissimum Seed Oil, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Sodium Citrate, Pongamia Pinnata Seed Extract, Salvia Hispanica Seed Oil, Macadamia Ternifolia Seed Oil, Fragrance (Parfum), Sclerotium Gum, b Ceramide NP, Citric Acid, Phenoxyethanol, Potassium Sorbate, Acetic Acid, Acetyl Hexapeptide-8, S-Palmitoylglutathione, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Sodium Phytate, Citronellol, Geranyl Acetate, Hydroxycitronellal, Limonene, Linalool, Linalyl Acetate, Tetramethyl Acetyloctahydronaphthalenes
    SizeNot stated
    SourceBrand's own product page
    Checked

    Common questions

    What kind of product is this?

    Perricone MD describes it as a firming and tightening face cream.

    What does it target?

    The page says it targets loss of firmness, skin elasticity, volume, and photodamage.

    Does it contain fragrance?

    Yes. The ingredient list includes fragrance (parfum).

    Which ingredients are highlighted?

    The product page highlights neuropeptides, biomimetic growth factor peptides, and ceramide NP alongside chia and macadamia oils.