Perricone MD

Neuropeptide Pore-Refining & Resurfacing Cream Cleanser

A cream cleanser with glycolic acid and salicylic acid for smoother-feeling pores.

Published · Updated

    What it is

    This cream cleanser is designed to refine the look of pores while smoothing dull, uneven texture. Perricone MD pairs glycolic acid with salicylic acid and peptide-supporting ingredients to target texture and congestion.

    Key ingredients

    • Glycolic acid: Helps loosen the look of dead-skin buildup and supports a smoother-feeling surface.
    • Lactobionic acid: A polyhydroxy acid that the brand uses to support gentle resurfacing.
    • Salicylic acid: Helps target clogged pores and rough texture.
    • Niacinamide: Supports the look of a more even, balanced complexion.
    • Peptides and fruit-cell extract: Support the brand’s smoothing and renewal claims.

    How to use

    Use this cream cleanser as the start of your daily cleansing routine. Perricone MD presents it as a pore-refining wash that can be used before the rest of your skincare steps.

    Who should be careful

    This formula includes fragrance and a fragrance-related ingredient, limonene. It also contains glycolic acid and salicylic acid, so anyone sensitive to exfoliating acids should review the current package list and patch test first. This is general product information, not medical advice.

    What the brand claims

    Perricone MD says this cleanser helps address clogged pores, dullness, and uneven texture. The page frames it as a resurfacing cream cleanser for a smoother-looking complexion.

    Manufacturer ingredient information

    Manufacturer ingredient list

    Water/Aqua/Eau, Sodium Cocoyl Glutamate, Cocamidopropyl Hydroxysultaine, Glycolic Acid, Decyl Glucoside, Glycerin, Butyrospermum Parkii (Shea) Butter, Glycol Distearate, Sodium Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trehalose, Lactobionic Acid, Sodium Hydroxide, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Citric Acid, Ethylhexylglycerin, Hexylene Glycol, Polyquaternium-73, Allantoin, Niacinamide, Dipotassium Glycyrrhizate, Fragrance (Parfum), Tetrasodium Glutamate Diacetate, Butylene Glycol, PEG-60 Almond Glycerides, Salicylic Acid, Sodium Hyaluronate, Malus Domestica Fruit Cell Culture Extract, Xanthan Gum, Glyceryl Stearate, Sodium Citrate, Ceteareth-25, Caprylic/Capric Triglyceride, Carbomer, Lecithin, Ceteareth-6, Coco-Glucoside, Sodium Lactate, Pterocarpus Marsupium Bark Extract, Nordihydroguaiaretic Acid, Oleanolic Acid, Sodium Metabisulfite, Stearyl Alcohol, Potassium Sorbate, Acetic Acid, Acetyl Hexapeptide-8, Biotin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Limonene

    Verified ingredient flags: Fragrance (Parfum); Limonene

    Source: https://www.perriconemd.com/p/neuropeptide-pore-refining--resurfacing-cream-cleanser/15763866/ (checked 2026-10-11).

    Check the current package ingredient list before use; manufacturer formulas may change. Ingredient flags are presence checks, not safety judgments.

    Sources

    We have not tested this product.

    What's on the label

    CategoryGel, Foam & Cream Facial Cleansers
    BrandPerricone MD
    Size6 fl oz
    FormCream cleanser
    TextureCreamy
    Key ingredientsGlycolic acid, lactobionic acid, salicylic acid, niacinamide, peptides
    Routine stepDaily facial cleanser
    Key ingredientNone stated
    Best forNot specified
    Fragrance freeNo
    Worth knowingFragrance (Parfum), Limonene
    Full ingredient listWater/Aqua/Eau, Sodium Cocoyl Glutamate, Cocamidopropyl Hydroxysultaine, Glycolic Acid, Decyl Glucoside, Glycerin, Butyrospermum Parkii (Shea) Butter, Glycol Distearate, Sodium Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trehalose, Lactobionic Acid, Sodium Hydroxide, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Citric Acid, Ethylhexylglycerin, Hexylene Glycol, Polyquaternium-73, Allantoin, Niacinamide, Dipotassium Glycyrrhizate, Fragrance (Parfum), Tetrasodium Glutamate Diacetate, Butylene Glycol, PEG-60 Almond Glycerides, Salicylic Acid, Sodium Hyaluronate, Malus Domestica Fruit Cell Culture Extract, Xanthan Gum, Glyceryl Stearate, Sodium Citrate, Ceteareth-25, Caprylic/Capric Triglyceride, Carbomer, Lecithin, Ceteareth-6, Coco-Glucoside, Sodium Lactate, Pterocarpus Marsupium Bark Extract, Nordihydroguaiaretic Acid, Oleanolic Acid, Sodium Metabisulfite, Stearyl Alcohol, Potassium Sorbate, Acetic Acid, Acetyl Hexapeptide-8, Biotin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Limonene
    SizeNot stated
    SourceBrand's own product page
    Checked

    Common questions

    What kind of cleanser is it?

    Perricone MD describes it as a pore-refining and resurfacing cream cleanser.

    Which actives are highlighted in the formula?

    The official ingredient list highlights glycolic acid, lactobionic acid, and salicylic acid, with niacinamide and peptides in the blend.

    Does it contain fragrance?

    Yes. The ingredient list includes fragrance (parfum) and limonene.

    How should it fit into a routine?

    The brand presents it as a daily facial cleanser to use during cleansing, before the rest of your routine.